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Interdisciplinary CompetenceMolecular Diagnostics
Know how in the analysis of genetic material.
For the benefit of patients.

Summary

Short information

Guideline-curated single gene sequence analysis according to the clinical suspicion TRAPS

ID
TS0310
Number of genes
1 Accredited laboratory test
Examined sequence length
1,4 kb (Core-/Core-canditate-Genes)
- (Extended panel: incl. additional genes)
Analysis Duration
on request
Material
  • EDTA-anticoagulated blood (3-5 ml)
Diagnostic indications

NGS +

 

Gene panel

Selected genes

NameExon Length (bp)OMIM-GReferenz-Seq.Heredity
TNFRSF1A1368NM_001065.4AD

Informations about the disease

Clinical Comment

Tumor necrosis factor receptor 1 associated periodic syndrome (TRAPS) is a periodic fever syndrome with arthralgia, myalgia + tender skin lesions for 1-3 weeks, associated with skin, joint, ocular + serosal inflammation, complicated by secondary amyloidosis

 

Synonyms
  • Alias: Hibernian fever, familial
  • Alias: Periodic fever, familial, autosomal dominant (TNFRSF1A)
  • Alias: TNF receptor-associated periodic syndrome (TNFRSF1A)
  • Alias: Tumor necrosis factor receptor 1 associated periodic syndrome (TNFRSF1A)
  • Alias: Tumornekrosefaktor-Rezeptor 1-assoziiertes periodisches Fieber-Syndrom (TNFRSF1A)
  • Allelic: Multiple sclerosis, susceptibility to, 5 (TNFRSF1A)
Heredity, heredity patterns etc.
  • AD
OMIM-Ps
ICD10 Code

Bioinformatics and clinical interpretation

No text defined