Deutsch
IllnessSubmikroskopische Chromosomen-Aberration
Summary
ID
AD0001
Number of genes
1
Accredited laboratory test
Examined sequence length
1,0 kb (Core-/Core-canditate-Genes)
- (Extended panel: incl. additional genes)
- (Extended panel: incl. additional genes)
Analysis Duration
on request
Material
- EDTA-anticoagulated blood (3-5 ml)
Diagnostic indications
Diagnostics via array CGH (array-based comparative genomic hybridization) is performed by simultaneously hybridizing fluorescence-labeled patient and control DNA on a carrier array with a large number of DNA probes. This technique is used to detect copy number changes of DNA fragments from a patient that are not detected by microscopic chromosome analysis. Losses of genomic regions (deletions) and gains (duplications) are shown in parallel examination. Frequent indications for array CGH diagnostics include questions regarding mental retardation, organ malformations, dysmorphic signs etc.
Gene panel
Selected genes
| Name | Exon Length (bp) | OMIM-G | Referenz-Seq. | Heredity |
|---|---|---|---|---|
| Genomweite Diagnostik | 999 |
| n.a. |
Informations about the disease
Synonyms
- Array diagnostics
- Array-based copy number analysis
- CGH-Analyse
- Chip-Diagnostik
- DNA Microarray Technology
Heredity, heredity patterns etc.
- n.a.
OMIM-Ps
- Multiple OMIM-Ps
ICD10 Code
Bioinformatics and clinical interpretation
No text defined