©istock.com/Andrea Obzerova
Interdisciplinary CompetenceMolecular Diagnostics
Know how in the analysis of genetic material.
For the benefit of patients.

IllnessMorbus Crohn, genetic predisposition


Short information

Comprehensive differential diagnostic panel for Morbus Crohn comprising 4 curated genes according to the clinical signs

Number of genes
4 Accredited laboratory test
Examined sequence length
0,0 kb (Core-/Core-canditate-Genes)
6,7 kb (Extended panel: incl. additional genes)
Analysis Duration
on request
  • EDTA-anticoagulated blood (3-5 ml)
Diagnostic indications




Gene panel

Selected genes

NameExon Length (bp)OMIM-GReferenz-Seq.Heredity

Informations about the disease

Clinical Comment

No ORPHA# because too frequent -

Inflammatory bowel disease with chronic relapsing intestinal inflammation subdivided into Crohn disease + ulcerative colitis phenotypes. M. Crohn may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon.


  • Alias: Crohn disease
  • Alias: Inflammatory bowel disease
  • Alias: Regional enteritis
  • Allelic: Autoimmune disease, multisystem, infantile-onset, 1 (STAT3)
  • Allelic: Blau syndrome (NOD2)
  • Allelic: Budd-Chiari syndrome, somatic (JAK2)
  • Allelic: Colchicine resistance (ABCB1)
  • Allelic: Diabetes, susceptibility to (IL6)
  • Allelic: Graft-versus-host disease, protection against (IL10)
  • Allelic: HIV-1, susceptibility to (IL10)
  • Allelic: Hepatitis B virus, susceptibility to (IL10RB)
  • Allelic: Hyper-IgE recurrent infection syndrome (STAT3)
  • Allelic: Immunodeficiency 29, mycobacteriosis (IL12B)
  • Allelic: Immunodeficiency 35 (TYK2)
  • Allelic: Intracranial hemorrhage in brain cerebrovascular malformations, susceptibility (IL6)
  • Allelic: Kaposi sarcoma, susceptibility to (IL6)
  • Allelic: Multiple sclerosis, susceptibility to, 1 (HLA-DRB1)
  • Allelic: Mycobacterium tuberculosis, protection against (IRGM)
  • Allelic: Parkinson disease 8 (LRRK2)
  • Allelic: Psoriasis, protection against (IL23R)
  • Allelic: Rheumatoid arthritis, progression of (IL10)
  • Allelic: Rheumatoid arthritis, susceptibility to (SLC22A4)
  • Allelic: Rheumatoid arthritis, systemic juvenile (IL6)
  • Allelic: Sarcoidosis, susceptibility to, 1 (HLA-DRB1)
  • Allelic: Yao syndrome (NOD2)
  • Carnitine deficiency, systemic primary (SLC22A5)
  • Crohn disease-associated growth failure (IL6)
  • Inflammatory bowel disease 1, Crohn disease (NOD2)
  • Inflammatory bowel disease 13 (ABCB1)
  • Inflammatory bowel disease 17, protection against (IL23R)
  • Inflammatory bowel disease 25, early onset, AR (IL10RB)
  • Inflammatory bowel disease 28, early onset, AR (IL10RA)
  • Inflammatory bowel disease [Crohn disease] 10 (ATG16L1)
  • Inflammatory bowel disease, Crohn disease 19 (IRGM)
  • Inflammatory bowel disease, Crohn disease 30 (CARD8)
  • Inflammatory bowel disease, infantile ulcerative colitis 31 (IL37)
Heredity, heredity patterns etc.
  • AD
  • AR
  • n.k.
  • Multiple OMIM-Ps
ICD10 Code

Bioinformatics and clinical interpretation

No text defined