Deutsch
IllnessLymphoma, follicular; prognosis
Summary
Short information
Comprehensive diagnostic panel for mutation detection in prognosis for Follicular Lymphomas - containing 9 curated genes
ID
FP0360
Number of genes
8
Accredited laboratory test
Examined sequence length
31,6 kb (Core-/Core-canditate-Genes)
- (Extended panel: incl. additional genes)
- (Extended panel: incl. additional genes)
Analysis Duration
on request
Material
- EDTA-anticoagulated blood (3-5 ml)
Diagnostic indications
NGS +
[Sanger]
Gene panel
Selected genes
| Name | Exon Length (bp) | OMIM-G | Referenz-Seq. | Heredity |
|---|---|---|---|---|
| ARID1A | 6858 | NM_006015.6 | AD | |
| BORCS8-MEF2B | 1281 | NM_005919.4 | Gen Fusion | |
| CARD11 | 3465 | NM_032415.7 | AD, AR | |
| CREBBP | 7329 | NM_004380.3 | AD | |
| EP300 | 7245 | NM_001429.4 | SMu | |
| EZH2 | 2256 | NM_004456.5 | AD, SMu | |
| FOXO1 | 1968 | NM_002015.4 | SMu, Gen Fusion | |
| TP53 | 1182 | NM_000546.6 | AD |
Informations about the disease
Clinical Comment
Non-Hodgkin lymphoma characterized by proliferation of B cells whose nodular structure of follicular architecture is preserved
Synonyms
- Allelic: Autoinflammatory syndrome, familial, Behcet-like (TNFAIP3)
- Allelic: Coffin-Siris syndrome 1 (ARID1B)
- Allelic: Coffin-Siris syndrome 2 (ARID1A)
- Allelic: Colorectal cancer, somatic (EP300)
- Allelic: Kabuki syndrome 1 (KMT2D)
- Allelic: Menke-Hennekam syndrome 1 (CREBBP)
- Allelic: Menke-Hennekam syndrome 2 (EP300)
- Allelic: Rubinstein-Taybi syndrome 1 (CREBBP)
- Allelic: Rubinstein-Taybi syndrome 2 (EP300)
- Allelic: Weaver syndrome (EZH2)
- B-cell non-Hodgkin lymphoma, high-grade (BCL7A)
- Follicular lymphoma, susceptibility to
- Leukemia/lymphoma, B-cell, 2 (BCL2)
- Lymphoma, B-cell (BCL6)
Heredity, heredity patterns etc.
- AD
- AR
- Gen Fusion
- SMu
OMIM-Ps
- Multiple OMIM-Ps
ICD10 Code
Bioinformatics and clinical interpretation
No text defined