IllnessKleine-Levin syndrome, differential diagnosis
Summary
Short information
Comprehensive differential diagnostic panel for Kleine-Levin syndrome comprising altogether 6 curated genes according to the clinical signs
ID
KP8273
Number of genes
5
Accredited laboratory test
Examined sequence length
0,0 kb (Core-/Core-canditate-Genes)
14,3 kb (Extended panel: incl. additional genes)
14,3 kb (Extended panel: incl. additional genes)
Analysis Duration
on request
Material
- EDTA-anticoagulated blood (3-5 ml)
Diagnostic indications
NGS +
Gene panel
Informations about the disease
Clinical Comment
Neurological disorder with relapsing-remitting episodes of hypersomnia associated with cognitive + behavioural disturbances
Synonyms
- Alias: Familiäre Hypersomnie
- Alias: Kleine-Levin hibernation syndrome
- Advanced sleep phase syndrome, familial, 1 (PER2)
- Advanced sleep phase syndrome, familial, 3 (PER3)
- Advanced sleep-phase syndrome, familial, 2 (CSNK1D)
- Cerebellar ataxia, deafness, narcolepsy, AD (DNMT1)
- Kleine-Levin syndrome associated with birth difficulties (TRANK1 genetic variants)
- Narcolepsy 7 (MOG)
- Neuropathy, hereditary sensory, type IE (DNMT1)
Heredity, heredity patterns etc.
- AD
OMIM-Ps
- Multiple OMIM-Ps
ICD10 Code
F51.1
Bioinformatics and clinical interpretation
No text defined