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Interdisciplinary CompetenceMolecular Diagnostics
Know how in the analysis of genetic material.
For the benefit of patients.

IllnessHyperlipoproteinaemia, type III

Summary

Short information

Curated single gene sequence analysis according to the clinical suspicion Hyperlipoproteinemia, type III

ID
HS0994
Number of genes
1 Accredited laboratory test
Examined sequence length
1,0 kb (Core-/Core-canditate-Genes)
- (Extended panel: incl. additional genes)
Analysis Duration
on request
Material
  • EDTA-anticoagulated blood (3-5 ml)
Diagnostic indications

NGS + SNP

Sanger

 

Gene panel

Selected genes

NameExon Length (bp)OMIM-GHeredity
APOE954AR

Informations about the disease

Clinical Comment

Combined hyperlipidemia type 3 with high levels of cholesterol + triglycerides, transported by intermediate density lipoproteins, high risk of progressive atherosclerosis + premature cardiovascular disease

 

Synonyms
  • Allelic: Alzheimer disease, protection against, due to APOE3-Christchurch (APOE)
  • Allelic: Alzheimer disease-2 (APOE)
  • Allelic: Coronary artery disease, severe, susceptibility to (APOE)
  • Allelic: Lipoprotein glomerulopathy (APOE)
  • Allelic: Macular degeneration, age-related (APOE)
  • Allelic: Sea-blue histiocyte disease (APOE)
  • Broad-beta disease (APOE)
  • Dysbetalipoproteinaemia (APOE)
  • Familial dyslipidemia type 3 (APOE)
  • Hyperlipidemia type 3 (APOE)
  • Hyperlipoproteinemia, type III (APOE)
  • Remnant hyperlipoproteinemia (APOE)
Heredity, heredity patterns etc.
  • AR
OMIM-Ps
ICD10 Code
E78.-

Bioinformatics and clinical interpretation

No text defined