IllnessHyperlipoproteinaemia, type III

Request form illness

Summary

Short information

Curated single gene sequence analysis according to the clinical suspicion Hyperlipoproteinemia, type III

HS0994

Number of genes

1 Accredited laboratory test

Examined sequence length

1,0 kb (Core-/Core-canditate-Genes)
- (Extended panel: incl. additional genes)

Analysis Duration

on request

Material

EDTA-anticoagulated blood (3-5 ml)

Diagnostic indications

NGS + SNP

Sanger

Gene panel

Selected genes

Name	Exon Length (bp)	OMIM-G	Referenz-Seq.	Heredity
APOE	954	107741	NM_000041.4	AD, AR

Informations about the disease

Clinical Comment

Combined hyperlipidemia type 3 with high levels of cholesterol + triglycerides, transported by intermediate density lipoproteins, high risk of progressive atherosclerosis + premature cardiovascular disease

Synonyms

Allelic: Alzheimer disease, protection against, due to APOE3-Christchurch (APOE)
Allelic: Alzheimer disease-2 (APOE)
Allelic: Coronary artery disease, severe, susceptibility to (APOE)
Allelic: Lipoprotein glomerulopathy (APOE)
Allelic: Macular degeneration, age-related (APOE)
Allelic: Sea-blue histiocyte disease (APOE)
Broad-beta disease (APOE)
Dysbetalipoproteinaemia (APOE)
Familial dyslipidemia type 3 (APOE)
Hyperlipidemia type 3 (APOE)
Hyperlipoproteinemia, type III (APOE)
Remnant hyperlipoproteinemia (APOE)

Heredity, heredity patterns etc.

OMIM-Ps

107741

ICD10 Code

Bioinformatics and clinical interpretation

No text defined