©istock.com/Andrea Obzerova
Interdisciplinary CompetenceMolecular Diagnostics
Know how in the analysis of genetic material.
For the benefit of patients.

IllnessDiabetes mellitus, type 2, susceptibility


Short information

Comprehensive differential diagnostic panel for Diabetes mellitus, type 2, susceptibility comprising 3 and altogether 27 curated genes according to the clinical signs

Number of genes
12 Accredited laboratory test
Examined sequence length
4,2 kb (Core-/Core-canditate-Genes)
17,0 kb (Extended panel: incl. additional genes)
Analysis Duration
on request
  • EDTA-anticoagulated blood (3-5 ml)
Diagnostic indications




Gene panel

Selected genes

NameExon Length (bp)OMIM-GReferenz-Seq.Heredity
GPD22184NM_000408.5AD, Sus
MTNR1B1089NM_005959.5AD, Sus
PDX1852NM_000209.4AD, Sus
HMGA1291NM_002131.4AD, Sus
HNF1B1674NM_000458.4AD, Sus
HNF4A1359NM_175914.4AD, Sus
IGF2BP21671NM_001007225.3AD, Sus
KCNJ111173NM_000525.4AD, Sus
NEUROD11071NM_002500.5AD, Sus
PPARG1518NM_015869.5AD, Sus

Informations about the disease

Clinical Comment

Diabetes type 2 usually occurs in adulthood; overweight + lack of exercise predispose; in many cases preventable by lifestyle changes


  • Alias: Diabetes mellitus, type 2, susceptibility to
  • Allelic: Diabetes mellitus, transient neonatal 3 (KCNJ11)
  • Allelic: Hyperinsulinemic hypoglycemia, familial, 2 (KCNJ11)
  • Allelic: Hypoinsulinemic hypoglycemia with hemihypertrophy (AKT2)
  • Diabetes mellitus, noninsulin-dependent (HNF4A)
  • Diabetes mellitus, noninsulin-dependent, susceptibility to (IGF2BP2, RETN)
  • Diabetes mellitus, type 2, susceptibility to (KCNJ11)
  • Diabetes mellitus, type II (AKT2)
  • Diabetes, permanent neonatal 2, with/-out neurologic features (KCNJ11)
  • Diabetes, type 2, susceptibility to (GPD2, MTNR1B, PDX1, TCFL2)
  • Fanconi renotubular syndrome 4, with maturity-onset diabetes of the young (HNF4A)
  • Growth retardation, developmental delay, facial dysmorphism (FTO)
  • MODY, type I (HNF4A)
  • Maturity-onset diabetes of the young, type 13 (KCNJ11)
  • Obesity, susceptibility to, BMIQ1 (FTO)
  • Renal cysts + diabetes syndrome (HNF1B)
  • Type 2 diabetes mellitus (HNF1B)
  • Type 2 diabetes mellitus, susceptibility to (NEUROD1, IRS1, HMGA1)
Heredity, heredity patterns etc.
  • AD
  • Sus
  • Multiple OMIM-Ps
ICD10 Code

Bioinformatics and clinical interpretation

No text defined