©istock.com/Andrea Obzerova
Interdisciplinary CompetenceMolecular Diagnostics
Know how in the analysis of genetic material.
For the benefit of patients.

IllnessDiabetes mellitus, type 2, susceptibility


Short information

Comprehensive differential diagnostic panel for Diabetes mellitus, type 2, susceptibility comprising 3 and altogether 27 curated genes according to the clinical signs

Number of genes
12 Accredited laboratory test
Examined sequence length
4,2 kb (Core-/Base-Genes)
17,0 kb (Extended panel)
Analysis Duration
on request
  • EDTA-anticoagulated blood (3-5 ml)
Diagnostic indications




Gene panel

Selected genes

NameExon Length (bp)OMIM-GHeredity
GPD22184AD and/or Ass
MTNR1B1089AD and/or Ass
PDX1852AD and/or AR and/or Dig and/or Sus
HMGA1291AD and/or Sus
HNF1B1674AD and/or Sus
HNF4A1359AD and/or Dig and/or Sus
IGF2BP21671AD and/or Ass
KCNJ111173AD and/or AR and/or Ass
NEUROD11071AD and/or AR
PPARG1518AD and/or Ass

Informations about the disease

Clinical Comment

Diabetes type 2 usually occurs in adulthood; overweight + lack of exercise predispose; in many cases preventable by lifestyle changes


  • Alias: Diabetes mellitus, type 2, susceptibility to
  • Allelic: Diabetes mellitus, transient neonatal 3 (KCNJ11)
  • Allelic: Hyperinsulinemic hypoglycemia, familial, 2 (KCNJ11)
  • Allelic: Hypoinsulinemic hypoglycemia with hemihypertrophy (AKT2)
  • Diabetes mellitus, noninsulin-dependent (HNF4A)
  • Diabetes mellitus, noninsulin-dependent, susceptibility to (IGF2BP2, RETN)
  • Diabetes mellitus, type 2, susceptibility to (KCNJ11)
  • Diabetes mellitus, type II (AKT2)
  • Diabetes, permanent neonatal 2, with/-out neurologic features (KCNJ11)
  • Diabetes, type 2, susceptibility to (GPD2, MTNR1B, PDX1, TCFL2)
  • Fanconi renotubular syndrome 4, with maturity-onset diabetes of the young (HNF4A)
  • Growth retardation, developmental delay, facial dysmorphism (FTO)
  • MODY, type I (HNF4A)
  • Maturity-onset diabetes of the young, type 13 (KCNJ11)
  • Obesity, susceptibility to, BMIQ1 (FTO)
  • Renal cysts + diabetes syndrome (HNF1B)
  • Type 2 diabetes mellitus (HNF1B)
  • Type 2 diabetes mellitus, susceptibility to (NEUROD1, IRS1, HMGA1)
Heredity, heredity patterns etc.
  • AD
  • AD and/or AR
  • AD and/or AR and/or Ass
  • AD and/or AR and/or Dig and/or Sus
  • AD and/or Ass
  • AD and/or Dig and/or Sus
  • AD and/or Sus
  • Multiple OMIM-Ps
ICD10 Code

Bioinformatics and clinical interpretation

No text defined